Novel F-18 Beta-Hydroxybutyric Acid Radiotracers for PET Imaging

Description

Researchers at the University of Alberta have synthesized novel beta-hydroxybutyric acid radiotracers for PET imaging using a 3 step radiosynthetic process. The compounds are designed to serve as radiofluorinated analogues of endogenous non-fluorinated metabolites. The biodistribution of the radiotracers in PET scans of normal mice show uptake in tissues that are difficult to visualize by […]

A Novel Method for CryoPreservation of Cells in Monolayers

Description

Researchers at the University of Alberta have developed a novel method to cryopreserve cells while adhered in a monolayer configuration. This method can preserve cells on a substrate and provide high post-thaw cell viability. Your company could then supply cryopreserved bioengineered cell monolayers directly in the desired configuration for immediate use.

 
Publication
Publication2018
Advantages

Allows cryopreservation of cells […]

Train-Triggered Alert System for Conditioning and Warning Wildlife

Description

Researchers at the University of Alberta have developed a novel, inexpensive, and compact system to alert wildlife to approaching trains, increasing the time available to avoid a collision.

Rail-caused mortality of wildlife is increasing with the footprint of railways and the speed of trains around the world, often occurring in protected areas with adjacent wildlife habitat […]

New Topical Therapy for Melanoma

Description

Dr. Afsaneh Lavasanifar and collaborators have developed a PCBCL–b-PEG-b-PCBCL (PolyGelTM) hydrogel formulation of silibinin which provides enhanced skin permeabiity and delayed release of silibinin under physiological conditions. In vitro and ex vivo findings suggest this PolyGel formulation of silibinin may be useful as a topical therapy for malignant melanoma.

PolyGel incorporated a relatively high amount of […]

Novel FOXM-1 inhibitors for diagnosis and treatment of cancer

Description

Researchers at the University of Alberta are utilizing their new insights into the mechanism of action of FOXM-1 inhibitors to design first in class oncology drugs targeting FOXM-1 protein. In addition, novel radiolabeled probes can detect FOXM-1 expressing tumor tissue for companion diagnostic purposes.

FOXM-1 is a transcription factor involved in cancer cell proliferation. Its expression […]

By |August 2nd, 2018|Licensing Opportunities|0 Comments

Novel SERS-Based Biosensing platform for prostate cancer

Description

Researchers at the University of Alberta have developed biogenic silver nanoparticles which can be used as plasmonic labels for enhanced spectroscopy applications. The nanoparticles can be modified with Raman active molecules either in situ or post production. The detection platform for biosensing targets the AR-V7 biomarker for metastatic castration resistant prostate cancer. The platform predicts […]

By |August 2nd, 2018|Licensing Opportunities|0 Comments

Hand-Held Device and Computer-Implemented Steering of a Percutaneously Inserted Needle

Description

Dr. Mahdi Tavakoli and his team at the University of Alberta have developed a novel hand-held device and methods to enable real-time assisted steering of percutaneously inserted needles, such as those used to deliver brachytherapy seeds to the prostate. The device is compact enough to fit within one hand and enables a surgeon to precisely and […]

Novel Radiation-Responsive Nanoparticles for Biomedical Applications

Description

Researchers at the University of Alberta in collaboration with Lakehead University have developed novel radiation-responsive block polymers for drug delivery. The nanoparticles are modified poly-L-glutamic acid (m-PGA) polymers which encapsulate one or multiple hydrophobic drugs, for example chemotherapeutic agents. Controlled release of drugs from the nanoparticles can be achieved by lysing the polymer by X-ray/gamma […]

By |March 20th, 2018|Licensing Opportunities|0 Comments

Flow Cytometry Sensing Using Diffracted Orders of a Grating

Description

Flow cytometry is a useful tool that employed in diagnoses of various blood diseases, basic research, clinical trials or even as a “cell sorter” instrument. Currently, flow cytometry involves an elaborate arrangement of mirrors and filters to split the signals from the device into the different wavelengths. This setup often requires several lasers and multiple […]

Off-Axis Spiral Phase Mirrors To Create Vortex Beams

Description

There has been an increased interest in taking advantage of the orbital angular momentum properties of light via helical wavefronts for various applications in manufacturing, imaging, and communications. By manipulating and enhancing these ‘vortex’ beams, new and more efficient applications in various industries can be realized using high powered or ultra-fast lasers. Previously, vortex beams […]

By |March 13th, 2018|Licensing Opportunities|0 Comments